University of Connecticut University of UC Title Fallback Connecticut

Mu-Ping Nieh

nieh_muhping_profileMu-Ping Nieh
Associate Professor

Department of Chemical & Biomolecular Engineering
97 North Eagleville Road, Unit 3136
Storrs, CT-06269-3136
Office: IMS-304
Phone: (860) 486-8708
Email:  Web:



  • Ph.D., University of Massachusetts, 1998


Research Focus

  • Nanostructural characterization of soft materials
  • Self-assembled targeting carriers for in-vivo delivery
  • Aligning freely standing relevant biomimetic model membrane
  • Structural phase diagrams of phospholipid mixtures (e.g., bicelles)
  • Polymer hydrogels, proton exchange membrane
  • Explosive detecting materials



  • NRC – Steacie Institute for Molecular Sciences (SIMS) “Significant Partnership” Award, 2008
  • Visiting Fellowship, Natural Sciences & Engineering Research Council of Canada, 2002-2004


Current Publications

Mahabir, S., Small, D., Li, M., Wan, W., Kucerka, N., Katsaras, J., Littrell, K., Nieh, M.-p.. “Growth Kinetics of Lipid-Based Nanodiscs to Unilamellar Vesicles- A Time-Resolved Small Angle Neutron Scattering (SANS) Study.” Biochim & Biophys. Acta – Biomembranes,1828 (3), 1025-1035. (2012).

Jang, H.-S., Wang, Y., Lei, Y., Nieh, M.-p.. “Controllable formation of pyrene (C16H10) excimers in polystyrene/tetrabutylammonium hexafluorophosphate films through solvent vapor and temperature annealing.” Journal of Physical Chemistry C, 117 (3), 1428-1435. (2012).

Hsu, C.-Y., Nieh, M.-p., Lai, P.-S.. “Facile Self-assembly of Porphyin-embedded Polymeric Vesicles for Theranostic Applications.” ChemComm, 48, 9343-9345. (2012).

M.-P. Nieh, P. Dolinar, N. Kučerka, S. R. Kline, L. M. Debeer-Schmitt, K. C. Littrell, J. Katsaras “Formation of Kinetically Trapped Nanoscopic Unilamellar Vesicles from Metastable Nanodiscs” Langmuir, 27, 14308-14316 (2011).

N. Kučerka, M.-P. Nieh, J. Katsaras “Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature” Biochim Biophys Acta – Biomembr. 1808, 2761-2771 (2011).

M.-P. Nieh, V. A. Raghunathan, G. Pabst, T. A. Harroun, K. Nagashima, H. Morales, J. Katsaras, and P. M. Macdonald “Temperature Driven Annealing of Perforations in Bicellar Model Membranes” Langmuir, 27, 4838-4847 (2011)

U. Iqbal, H. Albaghdadi, M.-P. Nieh, U. I. Tuor, Z. Mester, D. Stanimirovic,J. Katsaras, A. Abulrob “Small unilamellar vesicles: a platform technology for molecular imaging of brain tumors” Nanotechnology, 22, 195102 (2011)

Y. Guo, C. Mulligan, M.-P. Nieh “An Unusual Morphological Transformation of Rhamnolipid Aggregates Induced by Concentration And Addition of Styrene: A Small Angle Neutron Scattering (SANS) Study” Colloids Surf. A., 373, 42-50 (2011).

M.-P. Nieh, N. Kučerka, J. Katsaras “Formation Mechanism of Self-Assembled Unilamellar Vesicles” Can. J. Phys., 88, 735-740 (2010).

N. Kučerka, D. Marquardt, T. A. Harroun, M.-P. Nieh, S. R. Wassall, D. H. De Jong, L. V. Schäfer, S. J. Marrink, J. Katsaras “Cholesterol in bilayers with PUFA chains: Doping with DMPC or POPC results in sterol reorientation and membrane-domain formation” Biochemistry, 49, 7485–7493 (2010).