University of Connecticut |
Polymer Program SeminarMetrology for Tissue Engineering: Synthetic Reference Materials Development at NIST Monday, February 7, 2005 11:00 am , IMS Room 20 Tissue engineering is a developing field that will revolutionize medical treatment for patients who suffer the loss of an organ or tissue due to an accident or a disease by using biological principles to repair tissues and organs. While there are some tissue engineering products currently on the market, this industry faces many measurement challenges associated with FDA regulation, product quality control, and a basic understanding of the biological processes that these products are meant to stimulate and/or replace. The tissue engineering program at NIST focuses on the development and validation of reference conditions and measurement tools that are essential for meeting the metrology needs for this industry. I will review our recent research performed at NIST to develop synthetic reference materials. These include the development of a novel synthetic methodology to prepare well-defined peptide-polymer hybrids by combining solid phase peptide synthesis and ATRP synthesis, and the development of poly(2-hydroxyethyl methacrylate (HEMA) grafting density gradients as reference materials for tissue engineering applications.
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