Gas Chromatography Mass Spectroscopy – Agilent GCMS Systems

Agilent GCMS Systems 1
Agilent GCMS Systems 2
GCMS Readout (chromatogram)

Sample Requirements

Syringe Injection

  • Liquid (non-aqueous) or possibly gas
  • 0.5-5 µL per replicate
  • 10 ppm or higher desirable
  • Boiling point of entire sample <325℃

Thermal Desorption

  • Solid or highly viscous liquid (non-aqueous)
  • 0.2-5mg sample
  • Boiling point <325℃ (for component of interest)

Solid Phase MicroExtraction Headspace

  • Solid or liquid
  • Amount/concentration can vary
  • Boiling point <325℃ (for component of interest)

Summary of Technique

A sample is injected into a heated inlet, then the component molecules of the sample mixture are separated by interaction with a coated capillary column in the gas chromatograph. The separated molecules are detected with a mass spectrometer, allowing for identification.

Information Provided & Detection Limits

GCMS is typically considered the next step after infrared analysis. While infrared can rapidly detect the major functional groups present, GCMS has lower detection limits (potentially down to parts-per-trillion) and can identify the minor species present.


Electron Ionization

Lab Location and Contact Information

Lab Location: Science 1, G18A
Lab Manager: Capri Price