Yupeng Chen

Associate Professor

Department of Biomedical Engineering


  • Ph.D. (Nanomaterials and Nanomedicine) Brown University
  • MS (Biomedical Engineering) Brown University
  • BS (Chemistry) Fudan University

Research Focus

  • DNA-inspired Janus Base Nanomaterials
  • Tissue Chips, and Tissue Engineering
  • Drug and Gene Delivery
  • Nanomedicine

Honors and Awards

  • New Investigator Recognition Award (NIRA), Orthopaedic Research Society, San Antonio, 2013. (The top-one prize winner among 10 awardees selected from 40 finalists out of 545 applicants all over the world.)
  • Faculty Early Career Development (CAREER) Award, National Science Foundation, 2017.


X. Sun, Y. Chen, H. Yu, J. T. Machan, A. Alladin, J. Ramirez, R. Taliano, J. Hart, Q. Chen, R. M. Terek. Anti-miRNA Oligonucleotide Therapy for Chondrosarcoma. Mol Cancer Ther. 2019 Jul 24. pii: molcanther.1020.2018. doi: 10.1158/1535-7163.MCT-18-1020. PMID: 31341031

L. Zhou, A. Yau, H. Yu, L. Kuhn, W. Guo and Y. Chen. Self-assembled biomimetic Nano-Matrix for stem cell anchorage. J Biomed Mater Res A. 2020 Apr;108(4):984-991. doi: 10.1002/jbm.a.36875. PMID: 31904174

M. Sun, J. Lee, Y. Chen and K. Hoshino. Studies of nanoparticle delivery with in vitro bio-engineered microtissues. Bioactive Materials 2020; 5(4); 924-937. DOI: https://doi.org/10.1016/j.bioactmat.2020.06.016. PMID: 32637755

A. Yau, J. Lee, Y. Chen. Nanomaterials for Protein Delivery in Anticancer Applications. Pharmaceutics 2021, 13, 155. DOI: https://doi.org/10.3390/pharmaceutics13020155. PMID: 33503889

J. Lee, I. Sands, W. Zhang, L. Zhou, Y. Chen. DNA-inspired nanomaterials for enhanced endosomal escape. Proc Natl Acad Sci USA. May 11, 2021 118 (19) e2104511118. DOI: https://doi.org/10.1073/pnas.2104511118

Yupeng Chen
Contact Information
Mailing Address260 Glenbrook Road, Unit 3247, Storrs, CT 06269-3247
Office LocationA.B. Bronwell Building