University of Connecticut University of UC Title Fallback Connecticut

Devendra Kalonia

KaloniaDevendraDevendra Kalonia
Professor

Department of Pharmaceutical Sciences
69 North Eagleville Road
Storrs, CT 06269-3092
Phone: (860) 486-3655
Email: kalonia@uconn.edu

 

 

Education

  • Ph.D. University of Connecticut, Pharmaceutics
  • M.Pharm. Birla Institute of Technology and Science, Pharmaceutics
  • B.Pharm. Birla Institute of Technology and Science

 

Research Focus

High Concentration Proteins

  • Antibody Formulation Design
    • Protein-Protein Interactions
    • Viscosity/Rheology
    • Aggregation/Stability
    • Interfacial properties
  • Protein Solubility
    • Protein precipitation
    • Gelation
    • Opalescence

 

Current Publications

Yadav, S., Laue, T.M., Kalonia, D.S., Singh, S.N., Shire, S.J. (2012) “The Influence of Charge Distribution on Self-Association and Viscosity Behavior of Monoclonal Antibody Solutions, Molecular Pharmaceutics 9(4), 791-802.

Chari, R., Singh, S.N., Yadav, S., Brems, D.N., Kalonia, D.S. (2012) “Determination of the Dipole Moments of RNAse SA Wild Type and a Basic Mutant,” Proteins 80(4), 1041-52.

Yadav, S., Shire, S.J., Kalonia, D.S. (2012) “Viscosity Behavior of High-Concentration Monoclonal Antibody Solutions: Correlation with Interaction Parameter and Electroviscous Effects,” Journal of Pharmaceutical Sciences, 101(3), 998-1011.

Abbas, S.A., Sharma, V.K., Patapoff, T.W., Kalonia, D.S. (2012) “Opposite Effects of Polyols on Antibody Aggregation: Thermal Versus Mechanical Stresses,” Pharmaceutical Research 29(3), 683-94.

Printz, M., Kalonia, D.S., Friess, W. (2012) “Individual Second Virial Coefficient Determination of Monomer and Oligomers in Heat-Stressed Protein Samples Using Size-Exclusion Chromatography-Light Scattering,” Journal of Pharmaceutical Sciences 101(1), 363-72.

Yadav, S., Sreedhara, A., Kanai, S., Liu, J., Lien, S., Lowman, H., Kalonia, D.S., Shire, S.J. (2011) “Establishing a Link Between Amino Acid Sequences and Self-Associating and Viscoelastic Behavior of Two Closely Related Monoclonal Antibodies,” Pharmaceutical Research 28(7), 1750-64.