Dr. Luyi Sun Named a 2020 Presidential M1 Mentor by CCI

Dr. Luyi Sun
Dr. Luyi Sun

The Presidential M1 Mentorship Award Program was established to create a national model for best practices in mentorship and formalize mentorship as an academic discipline. The award seeks to establish a cadre of accomplished UConn faculty who will deliver mentorship to racially and ethnically underrepresented individuals along the biomedical science pipeline.

Dr. Luyi Sun, Director of the IMS Polymer Program, and Professor of Chemical and Biomolecular Engineering was named a 2020 recipient of the M1 Mentorship Award.

Dr. Sun joined the UConn faculty as an associate professor in 2013 and by 2018 had been promoted to full professor. His research focuses on the design and synthesis of nanostructured materials for various applications. He has served as major advisor to numerous Ph.D. graduates. His group currently includes graduate students, visiting scholars, and a postdoctoral researcher.

Funding for the Presidential M1 Mentorship Award Program covers up to 25% of protected time for mentoring activities, including mentorship of individual students as well as participation in the development and execution of various mentorship initiatives. In addition, up to $5,000 will be allocated to the development of new and innovative initiatives focused on student-related activities that promote their academic growth and increase the number of students in the pipeline.

UConn Course Focuses on the Chemistry of Wine

Dr. Thomas Seery
Dr. Thomas Seery

It’s a big world out there when it comes to wine, the libation made from fruit of the vine.

Enter Dr. Thomas Seery, IMS faculty member and Associate Professor of Chemistry, who teaches a class on “Understand-ing Wine Chemis-try.”

Seery lands in the right place at the right time when he makes his connections. He’s been teaching this class in Shanghai in the summers. Through a series of fortunate events, including passport control, meeting wives of professors and a group of scholars coming to UConn, Seery brings his interests in wine to the college community and beyond.

Throughout my Zoom interview, I heard words like tannins, retronasal, terpene and umami. Umami is a category of taste in food. I thought there were only four basic tastes, but there are more. It’s related to the flavor of glutamates.

Read the full story at The Chronicle

UConn Researcher Invents Nanoparticle for Overcoming Leukemia Treatment Resistance

Dr. Xiuling Lu (left) and Dr. Rajeswari Kasi
Dr. Xiuling Lu (left) and Dr. Rajeswari Kasi

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.

One of the largest problems with cancer treatment is the development of resistance to anticancer therapies. Few FDA-approved products directly target leukemia stem cells, which cause treatment-resistant relapses. The only known method to combat their presence is stem cell transplantation.

Leukemia presents unique treatment challenges due to the nature of this form of cancer. The disease affects bone marrow, which produces blood cells. Leukemia is a cancer of the early blood-forming cells, or stem cells. Most often, leukemia is a cancer of the white blood cells. The first step of treatment is to use chemotherapy to kill the cancerous white blood cells, but if the leukemia stem cells in the bone marrow persist, the cancer may relapse in a therapy-resistant form.

Fifteen to 20% of child and up to two thirds of adult leukemia patients experience relapse. Adults who relapse face a less-than 30% five-year survival rate. For children the five-year survival rate after relapse is around two thirds. When relapse occurs, chemotherapy does not improve the prognosis for these patients. There is a critical need for scientists to develop a therapy that can more effectively target chemotherapy-resistant cells.  Read the full UConn Today story.

Dr. Chris Monteleone: Reflections on an IMS Ph.D. Graduate

by Osker Dahabsu, Institute of Materials Science

Dr. Chris Monteleone
Dr. Chris Monteleone

Dr. Christopher Monteleone completed his final defense and Ph.D. in Materials Science in May 2020. Chris began his education in UConn’s Chemical Engineering undergraduate program in 2010. During his sophomore year he was offered a research position in the ceramic’s laboratory of Dr. Steven L. Suib. The lab’s focus is coatings deposited by chemical vapor deposition for composites. Interest in these materials and processing led Chris to pursue minor degrees in both Chemistry and Materials Science & Engineering.

Chris was encouraged to leave UConn for graduate school, however after some investigating, he realized his current lab was conducting cutting edge research that was unmatched and could lead him to a career. He remained at UConn to complete his Ph.D. in Materials Science. Chris’s thesis title was, “Design of Materials and Processing Methods for High Temperature Composites.”

Chris said he’s “grateful for the support he received at both IMS and Chemistry.” The open collaborative attitude helped him grow as a scientist and make achievements that might otherwise be impossible. Outside of research, Chris was offered an opportunity helping the mechanical testing and microscopy labs at IMS. This gave him experience in both professional communications and writing technical reports, excellent preparation for an industrial position.

Chris recently began his career as a Materials Engineer at the Rolls Royce High Temperature Composites lab in Cypress, California.

UConn, Army Research Lab Collaborate on New Portable, Renewable Energy Technology

scanning electron microscope image of the nanostructured Iridium oxide
A scanning electron microscope image of the nanostructured Iridium oxide, colored to represent the catalytic combustion studied by UConn and the Army researchers. (Courtesy of the Army Research Lab)

UConn’s Associate Dean for Research and Industrial Partnerships, S. Pamir Alpay, and Yomery Espinal ’18 Ph.D. (ENGR) have published a paper on a novel portable pyroelectric technology in Cell Reports Physical Science with support from the Army Research Laboratory.

Pyroelectric energy research is focused on how to generate energy from heat that would otherwise be wasted in a catalytic chemical reaction.

When pyroelectric materials are heated, their polarization changes, leading to an electron flow that generates energy. These materials are commonly used in household devices like motion sensor lights, which detect body heat to determine when someone is near.

nytime there is a catalytic reaction, heat is generated. These devices harness that heat and use it as energy. For example, a combustion engine in a car produces heat that, with this kind of technology, could be used to power the electrical functions of the car that otherwise rely on battery power.

The Army Research Lab (ARL) is particularly interested in this technology because it can provide more power with less weight, which is important for soldiers carrying heavy bags.

While scientists have been experimenting with pyroelectric power for decades, the technology proposed in this paper is completely novel.

“Something like that doesn’t exist,” Alpay says. “It would give you the opportunity to recover some things that just go to waste.”

Read the full UConn Today Story

IMS Welcomes Dennis Ndaya as Manager of Thermal Analysis Lab

Dr. Dennis Ndaya
Dr. Dennis Ndaya

On June 5, Dr. Dennis Ndaya became the new manager of the Thermal Analysis Laboratory, replacing Dr. Laura Pinatti who retired in May.

Dr. Ndaya earned his Ph.D. in chemistry from UConn in December 2019 under the advisemnt of Dr. Rajeswari Kasi. He received his M.Sc. in environmental chemistry from the University of Nairobi, Kenya.

His research has been published in such journals as International Journal of Pharmaceutics and Polymer Chemistry. Additionally, he has presented his research at the American Chemical Society where he received the Distinguished Poster Award in August 2015.

Dr. Ndaya’s research interests include synthetic methods, structural characterization, and thermal-mechanical analysis and microscopy. He has served on the IMS Safety Committee, and has served as a student mentor to high school, undergraduate, and graduate students on a variety of research projects, as well as serving as Head of the Department of Physical and Biological Sciences for the Pumwani Girls High School in Kenya.

IMS is proud to welcome Dr. Ndaya.

Dr. S. Pamir Alpay Named UConn Board of Trustees Distinguished Professor

Dr. S. Pamir Alpay
Dr. S. Pamir Alpay

Dr. S. Pamir Alpay, IMS faculty member and Associate Dean for Research and Industrial Partnerships, has been named a Board of Trustees Distinguished Professor.

The award recognizes faculty who have achieved exceptional distinction in scholarship, teaching, and service while at the University of Connecticut and has been awarded annually since 1998.

In addition to being associate dean, Alpay is the General Electric Professor in Advanced Manufacturing in the Department of Materials Science and Engineering and the Executive Director of UConn Tech Park, where he serves as UConn’s chief ambassador to industry and government agencies in building industry-responsive and economically important initiatives based on UConn’s strengths in applied research. In this role, he has excelled in outreach, having hosted workshops and symposia connecting over 500 professionals and government leaders on current topics ranging from sustainability, cybersecurity, energy, advanced manufacturing and support for small/medium size businesses. Read the full School of Engineering Story.

Dr. Laura Pinatti Retires

Dr. Laura Pinatti
Dr. Laura Pinatti

Dr. Laura Pinatti, manager of the IMS Thermal Analysis Laboratory, is soft-spoken and avoids the spotlight but she is also funny and caring, devoted to family, and amazing at her job. After 20 years working for the IMS Industrial Affiliates Program, Laura retired at the end of April. IMS News reached out to Dr. Pinatti with a few questions.

How did you come to the sciences and, specifically, analysis and characterization?
When the job for a research assistant in the thermal lab opened up in 2000 I jumped at the opportunity. My youngest had just turned 5 and it was time to get back to work. I couldn’t have found a better place to spend the next 20 years.

What did you like most about your job in IMS?
Working for IMS and for the IAP has been challenging and stimulating with always something new to keep it interesting. I loved working with our team to define and solve the ever-increasing complexity of issues that industry continue to face.

You’ve retired in the age of coronavirus where we are working and socializing remotely.  Of course there are plans to celebrate you when it is safe, but does having such a major event in these times feel different than what you expected?
Retiring when everything is shut down is obviously not how I expected to say goodbye.  I would have liked to shake some hands and share some hugs.

How will you remember your time in IMS?
I, of course, also enjoyed meeting and working with the all the graduate students over the years. Getting to know them, working with them on the instruments and learning about their research added a whole new layer of enjoyment to my life at IMS. But what I am going to miss most is chatting with the friendly faces in the halls and offices throughout IMS.

Do you have any special plans for your retirement years?
I am looking forward to a no-obligation, nowhere-to-be sort of retirement.  My priority is my family and my health and some road trips to new places now and then.


Recent Ph.D. Graduate Reflects on Experience as IMS Polymer Program Student

Dr. Deepthi Varghese
Dr. Deepthi Varghese

After completing a Master’s Degree in Biochemistry from St. Josephs Arts & Science College in Bangalore, India, Deepthi Varghese joined the UConn Chemistry graduate program in the fall semester of 2014. After hearing brief research presentations from the chemistry departmental faculty, she became interested in Polymer Science with Prof. Douglas Adamson, an unexpected diversion from her initial plans for a career in biochemistry into a field in which she had no experience.

Although the lack of experience created a steep learning curve, Deepthi embraced this new research direction. While she faced challenges during the first two years, looking back, Deepthi says that she gained far more knowledge than expected, including polymer science, electro chemistry, and setting up scientific research laboratories.

Deepthi also struggled with many challenges regarding science including the fact that experiments are more likely to fail than succeed; science takes far more time than initially expected; and there is never enough time to accomplish everything. Lessons like this can be applied to all aspects of life, business, and art, as well as science.

In addition to the science, Deepthi has increased her knowledge of communications, independent learning, and keeping an open mind to feedback from all sources. She realized that you never know who will have valuable knowledge.

“Keeping an open ear and open mind allows you to learn from faculty, technicians, graduate students, and undergraduate students as well,” Deepthi says. She noted that undergraduates, especially those from outside disciplines, are also able to contribute bits of knowledge to the scientific challenges of the day.

Deepthi became involved with UConn organizations, the South Asia Community (Tarang) and the Graduate School Senate, where she was treasurer and president, respectively. This experience helped her learn organizational leadership.

Looking back on her graduate experience at UConn, Deepthi says that she grew as a scientist as well as a person. She had a number of unexpected experiences that changed her in many ways, all positive. In November, 2019, Deepthi started her professional career as a TD Etch Module Engineer at Intel, Hillsboro, Oregon.

Dr. Challa V. Kumar Presents Research in Australia

Dr. Challa V. Kumar with Australian Education Minister Dan Tehan
Dr. Challa V. Kumar with Australian Education Minister Dan Tehan

Dr. Challa V. Kumar presented an invited Institute Lecture at the Australian Institute of Innovative Materials, University of Wollongong, Australia.

Dr. Kumar was selected for a Fulbright US-Australia Research Excellence Award in 2019 and has been conducting and presenting his research focused on 3D printing of enzymes to make progress toward the realization of Biobatteries. These batteries are intended to use sugar to power personal electronics.