Yongku Cho

Associate Professor

Department of Chemical and Biomolecular Engineering

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Education

Ph.D., University of Wisconsin-Madison (2010)

Research Focus

• Protein Engineering
• Antibody Engineering
• Alzheimer’s Disease
• Optogenetics

Awards and Honors

• Alzheimer’s Association – New Investigator Grant (2019)
• American Chemical Society Best of BIOT Award (2016)
• NARSAD Young Investigator Grant (2014)
• NIH Genomic Sciences Training Program Fellow (2007-2010)
• Gold Medal in Biochemical Engineering Competition sponsored by the Korean Institute of Chemical Engineers (KIChE) (2004-2007)
• Samsung Scholarship (2004-2006)

Publications

Yeast biopanning against site-specific phosphorylations in tau
Protein Engineering Design & Selection, 2023
Arbaciauskaite, M., Pirhanov, A., Ammermann, E., Lei, Y., Cho, Y.K.*
DOI:10.1093/protein/gzad005

Depth-multiplexed ptychographic microscopy for high-throughput imaging of stacked bio-specimens on a chip
Biosensors and Bioelectronics, 2023
Chengfei Guo, Shaowei Jiang, Liming Yang, Pengming Song, Azady Pirhanov, Ruihai Wang, Tianbo Wang, Xiaopeng Shao, Qian Wu, Yong Ku Cho, Guoan Zheng*
DOI:10.1016/j.bios.2022.115049

Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion
bioRxiv, 2022
Wang, S., Jiang, S., Zheng, G., Cho, Y.K.*
DOI:bioRxiv

Degradation-driven protein level oscillations in the yeast Saccharomyces cerevisiae
Biosystems, 2022
Mahrou, B.*, Pirhanov, A., Alijanvand, M., Cho, Y.K.*, Shin, Y.-J.
DOI:10.1016/j.biosystems.2022.104717

High specificity antibodies and detection methods for quantifying phosphorylated tau from clinical samples
Antibody Therapeutics, 2021
Arbaciauskaite, M., Lei, Y., Cho, Y.K.*
DOI:10.1093/abt/tbab004

Optogenetics in Sinorhizobium meliloti enables spatial control of exopolysaccharide production and biofilm structure
ACS Synthetic Biology, 2021
Pirhanov, A., Bridges, C.M., Goodwin, R.A., Guo, Y-S., Furrer, J., Shor, L.M., Gage, D.J., Cho, Y.K.*
DOI:10.1021/acssynbio.0c00498

Yeast surface display of full-length human microtubule-associated protein tau
Biotechnology Progress, 2020
Wang, S., Cho, Y.K.*
DOI:10.1002/btpr.2920