University of Connecticut University of UC Title Fallback Connecticut

Syam Nukavarapu

nukavarapuSyam_wSyam Nukavarapu
Associate Professor

UConn Health Center
263 Farmington Avenue
Farmington, CT 06030
Phone: (860) 486-4183
Email:  Web:


  • Post doctoral felow in Materials Science – Lehigh University, 2003-2005
  • Ph.D in Materials Science & Engineering – Indian Institute of Science, 1998 – 2003
  • MSc. in Chemistry , University of Hyderabad, 1996 – 1998


Research Focus

  • Polymer-hydrogel matrices for tissue engineering
  • Oxygen tension controlled matrices for enhanced bone regeneration
  • Engineering bone-cartilage interface
  • Advanced composite and structure design for tissue engineering and regenerative medicine
  • Clinically relevant tissue engineering methods



  • Inter-Campus Research Incentive Grant Award, University of Connecticut, CT, 2009
  • University Grants Commission Fellowship, Indian Institute of Science, India, 1998-2003
  • Post Doctoral Fellow, Orthopedic Surgery, University of Virginia, 2005-2008
  • Post Doctoral Fellow, Materials Science & Engineering, Lehigh University, 2003-2005


Current Publications

Nukavarapu SP, Dorcemus D. “Osteochondral Tissue Engineering: Current Strategies and Challenges.” Biotechnology Advances, 2012 [Epub ahead of print].

Igwe J, Mikael P, Nukavarapu SP. “Design, Fabrication and In Vitro Evaluation of a Novel Polymer-Hydrogel Hybrid Scaffold for Bone Tissue Engineering.” J Tissue Eng Regen Med. 2012 [Epub ahead of print]

Amini AR, Adams D, Laurencin CT, Nukavarapu SP. “Optimally Porous and Biomechanically Compatible Scaffolds for Large Area Bone Regeneration.” Tissue Eng Part A. 2012; 18:1376-88.

Amini AR, Laurencin CT, Nukavarapu SP. “Differential Analysis of Peripheral Blood- and Bone Marrow-Derived Endothelial Progenitor Cells for Enhanced Vascularization in Bone Tissue Engineering.” J Orthop Res. 30, 1507-15, 2012.

Amini AR, Laurencin CT, Nukavarapu SP. “Bone Tissue Engineering: Recent Advances and Challenges.” Crit Rev Biomed Eng. 40(5), 363-408, 2012.

Nukavarapu SP, Amini AR. “Optimal Scaffolds and Effective Progenitor Cells for the Regeneration of Vascularized Bone.” IEEE Engineering in Medicine and Biology, 2464-2467, 2011.

Mikael P and Nukavarapu SP. “Functionalized Carbon Nanotube Composite Scaffolds for Bone Tissue Engineering: Prospects and Progress.” Journal of Biomaterials and Tissue Engineering. 1, 76-85, 2011.

Jiang T, Nukavarapu SP, Deng M, Jabbarzadeh E, Kofron MD, Doty SB, Abdel-Fattah WI, Laurencin CT. “Chitosan-Poly(Lactide-Co-Glycolide) Microsphere Based Scaffolds for Bone Tissue Engineering: In Vitro Degradation and In Vivo Bone Regeneration Studies,” Acta Biomaterilia 6, 3457-70, 2010.